After Pat Garrett kills Billy the Kid, Billy's look-alike Roy Rogers arrives and is mistaken for him. Although a murderer, Billy was on the side of the homesteaders against the large ranchers. As Billy's death is unknown, Roy gets Garrett to let him pose as Billy to continue the fight, but without the killing.

In his starring debut, Roy gets elected to Congress in order to bring water to the ranchers in his district. In Washington, he learns he needs the backing of a key congressman and gets that man to go west for an inspection trip. When the congressman is initially unimpressed, Roy gets the inspection party stranded without water to show the true conditions.

A cowboy is wrongfully accused of murder. He winds up in Harlem, where he assumes the identity of a preacher-turned-gangster who looks like him. He infiltrates the gang to catch the men who framed him.

When he swaps horses with the Tombstone Kid — a wrongly accused man on the run from the law — singing cowboy Tex Randall gets arrested by the local sheriff in a case of mistaken identity.

Gene and Frog set out to find out who has been causing the accidents at a dam construction site.

The Rancho Grande, a Texas border ranch, cut off from the law by a gang of outlaws led by ranch foreman Bart Lane, who is holding the elderly owner of the ranch, Sarah Burton, a prisoner. Tex Lowery, an undercover Texas Ranger, rescues Martha Williams, a nurse sent for by the ailing Sarah, from a stagecoach holdup by Lane's henchmen. He later convinces Laner that he is a wanted outlaw named Ed Carter, and gains entry to Rancho Grande. But the real Ed Carter shows up.

A wagon train heads west from Independence, Mo., along the Oregon Trail, led by proud cowboy Clint Belmet. On board are feisty young widow Nancy Wellington and her toddler, Sonny, as well as the older Abby Masters, who begins a romance with scout Jim Burch. Along the way, the wagon train battles Indians led by Kenneth Murdock, a trapper who doesn't welcome competition for Oregon's lucrative fur trade. Wagon Wheels is a 1934 remake of 1931's Fighting Caravans, using stock footage from the original.

Hanson is using Bobby's carrier pigeons to receive messages. His man Slim shoots them down before they reach Bobby. When Slim is injured, Ranger Daniels posing as a drunk gets the job. He misses the next pigeon on purpose and gets the message from Bobby. But his identity has now become known and the gang rides to get him.

Storm is out to wreck Ace's stage line. When Tex arrives to help Ace, Storm brings in hired killer Mule Bates. But Tex and Bates know each other and the two devise a plan to fool Storm.

Gridley is mining silver from an old Mexican mine and bringing it into the USA thru a passage into his worthless mine. Border guard Rogers suspects Gridley and finally finds the secret entrance to the Mexican mine. He sends Lee Madison for help only to have her captured by Gridley. Trigger brings help that takes care of Gridley's men and now Roy has to rescue Madison.

Anchor is building a railroad and to get cheap labor he gets Black Hawk's Indians to attack and burn the incoming wagon train. This forces the settlers to work for Anchor and he pays them in devalued scrip. When Rex figures out Anchor's swindle, Anchor gets Black Hawk to capture him. When Anchor turns on Black Hawk and shoots him, Black Hawk gets a chance to repay a debt to Rex.

Scanlon is pulling off a land swindle by selling lots in a ghost town claiming the power company is bringing in a line. As a bonus he throws in shares in a worthless gold mine. Gene is on to Scanlon and tries to get him to buy back the deeds by salting the mine with gold. But when a new vein is really discovered Gene has to stop the sales but is trapped in the mine by Scanlon's men.

Saunders with his Cattlemen's Protective Agency is running roughshod over the ranchers. Lawyer Larry Kimball is fighting him but he needs a rancher that will stand up with him against Saunders. He finds him when Lou Gehrig retires from baseball to take up ranching. Lou expects to relax on his ranch but quickly joins Larry in the fight.

Gen. Ulysses S. Grant has a job for Wild Bill Hickok (George Houston) and his sidekick (Al St. John).

Gene and Frog arrive with a herd of horses for Gene'e brother, a diamond prospector whose work has attracted the interest of a bunch of badguys.

A story of cattle rustling and double identities.

In a wild west community populated entirely by residents with dwarfism, the Larson and Preston familes have been in a generations-long feud, recently strained by the actions of cattle rustler and overall devious criminal Bat Haines. Buck Larson, the hero of our tale, takes on Haines, and tries to win the heart of Nancy Preston while resolving the tensions between his and her families.

A wounded archaeologist crawls into the camp of three kindhearted cowboys. When the cowboys bring him to a nearby trading post, he's murdered after he lets slip a secret about a hidden cave. Investigating his death, Ken and his friends encounter a land dispute between a pair of neighboring ranches, an arrogant German baron and a mysterious shack that houses a great secret.

Americans come west to California in the hope of peaceful settlement. Roy and Gabby sing a duet: "We're Not Coming Out Tonight." Other songs include "Sundown on the Rangeland" and "Ride on Vaquero."

Cowboy Larry O'Day and his sidekick Lucky Smith happen upon a distraught Barbara Hartwell, who is about to be arrested for the murder of her uncle. With Barbara behind bars, Larry is determined to find the real killer and soon finds himself in the middle of a mystery involving crazed German entomologists and a smuggling ring bringing Chinese "picture girls" across the Mexican border for sale to wealthy Chinese bachelors.

"Nevada" and "Weary" Pierce hijack the loot taken in a bank hold-up by Les Setter, and his gang. They escape from Sheriff Jim Henry Warner. U. S. government horse-buyer David Ward is killed by Settler's men and Settler takes his papers and goes to the ranch of Blaine and asks for the horses Ward was to buy, promising payment from the government later. He also takes an interest in Ina Blaine, much to the resentment of her sweetheart Ben Ide. "Nevada" and "Weary" are hired for the horse round-up but Setter has them and Ben arrested on a fake charge.

Stony's brother George has been accused of murder and the Mesquiteers have returned to prove his innocence. But they find that Harvey rules the town along with his stooge Sheriff Gray and that George won't get a fair trial.

Dare Rudd takes a shine to his cattleman cousin Tom's girlfriend who asks Tom to hire Dare to head the big cattle drive. Dare loses the money for the drive to cardsharps, but Tom wins it back, but Dare must save Tom's life.

A crooked real estate manipulator sells worthless land on mortgage to flood refugees, then tries to profit by reselling the land to the state, committing murder in the process, as the Three Mesquiteers work to bring him and his gang to justice.

Sandy Doyle, gambler and political chief of a small border town, seeks to gain control of the Bar-X Ranch, owned by Rufe Rickson, to further some undercover activities of his own. He counts on Rickson's inability to stay away from gambling as the means to his ultimate success. Government investigator Oliver Shea and his assistant, Dan Haggerty, start a fight in Doyle's place when they see Rickson being cheated and are invited to the Bar-X where Oliver and Helen Rickson, Rufe's daughter, discover interest in each other and Dan finds himself pursued by Bell, the ranch cook. Sheriff Larson brings the prize money for the $5,000 race of the Rodeo Association, and that night it is stolen.

Tex is up against a group of hooded outlaws. When he shoots one, he uses the hood to infiltrate the gang. Almost caught by them, he escapes only to be arrested by the Sheriff who thinks he's one of the gang.

As the sheriff of a small western town, Autry sings his way into a relationship with Eleanor, a singer from a Chicago nightclub who earlier witnessed a murder.

Wanted by the law in New York, Dr. Steve Kells heads west and arrives in an area controlled by an outlaw gang known as the Border Legion. When the gang's boss is wounded, they kidnap Kells and force him to remove the bullet. Not allowed to leave and being a wanted man, he joins the gang. Now wanted as a gang member also, he nevertheless plans a raid that will lead the entire gang into a trap.

Trouble in Colorado is tying up Union troops needed back east during the Civil War and Lieut. Burke is sent to investigate. Macklin and his gang are causing the problems and Capt. Mason joins them. When Burke catches up with them he also finds Mason, his brother.

Chet Kasedon is after the Indians hidden gold mine but Chief Moya will not reveal it's location. He has also hired mining engineers Gale and Mortimer to locate the mine. When Gale sees Kasedon's cruelty to Moya, he switches sides.